Afatinib vs Dexamethasone

## Afatinib vs Dexamethasone: Overview

This comparison examines the pharmacological differences between **Afatinib** and **Dexamethasone**.

## Mechanism of Action

**Afatinib**: Irreversible covalent inhibitor of ErbB family (EGFR/HER1, HER2, HER4) tyrosine kinases.

**Dexamethasone**: Potent synthetic glucocorticoid.

## Pharmacokinetics

**Half-life**: Afatinib — 37 hours; Dexamethasone — 36-54 hours.

## Chemical Properties

**Molecular Formula**: Afatinib — C24H25ClFN5O3; Dexamethasone — C22H29FO5.

**Molecular Weight**: Afatinib — 485.9400 g/mol; Dexamethasone — 392.4610 g/mol.

**Type**: Afatinib — Small molecule; Dexamethasone — Small molecule.