Allopurinol vs Trimethoprim

## Allopurinol vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Allopurinol** and **Trimethoprim**.

## Mechanism of Action

**Allopurinol**: Xanthine oxidase inhibitor reducing uric acid production.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Allopurinol — 1-2 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Allopurinol — C5H4N4O; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Allopurinol — 136.1120 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Allopurinol — Small molecule; Trimethoprim — Small molecule.