Atezolizumab vs Pembrolizumab

## Atezolizumab vs Pembrolizumab: Overview

This comparison examines the pharmacological differences between **Atezolizumab** and **Pembrolizumab**.

## Mechanism of Action

**Atezolizumab**: Fully human anti-PD-L1 IgG1 monoclonal antibody blocking PD-L1 interaction with PD-1 and B7.1.

**Pembrolizumab**: Anti-PD-1 monoclonal antibody restoring anti-tumor immunity.

## Pharmacokinetics

**Half-life**: Atezolizumab — 27 days; Pembrolizumab — 26 days.

## Chemical Properties

**Type**: Atezolizumab — Antibody; Pembrolizumab — Antibody.