Bupropion vs Trazodone

## Bupropion vs Trazodone: Overview

This comparison examines the pharmacological differences between **Bupropion** and **Trazodone**.

## Mechanism of Action

**Bupropion**: Norepinephrine-dopamine reuptake inhibitor (NDRI).

**Trazodone**: Serotonin antagonist and reuptake inhibitor (SARI).

## Pharmacokinetics

**Half-life**: Bupropion — 21 hours; Trazodone — 5-9 hours.

## Chemical Properties

**Molecular Formula**: Bupropion — C13H18ClNO; Trazodone — C19H22ClN5O.

**Molecular Weight**: Bupropion — 239.7420 g/mol; Trazodone — 371.8640 g/mol.

**Type**: Bupropion — Small molecule; Trazodone — Small molecule.