Canagliflozin vs Captopril

## Canagliflozin vs Captopril: Overview

This comparison examines the pharmacological differences between **Canagliflozin** and **Captopril**.

## Mechanism of Action

**Canagliflozin**: Selective SGLT2 inhibitor reducing renal glucose reabsorption and lowering blood glucose.

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

## Pharmacokinetics

**Half-life**: Canagliflozin — 10.6 hours; Captopril — 1.9 hours.

## Chemical Properties

**Molecular Formula**: Canagliflozin — C24H25FO5S; Captopril — C9H15NO3S.

**Molecular Weight**: Canagliflozin — 444.5170 g/mol; Captopril — 217.2850 g/mol.

**Type**: Canagliflozin — Small molecule; Captopril — Small molecule.