Canagliflozin vs Sildenafil

## Canagliflozin vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Canagliflozin** and **Sildenafil**.

## Mechanism of Action

**Canagliflozin**: Selective SGLT2 inhibitor reducing renal glucose reabsorption and lowering blood glucose.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Canagliflozin — 10.6 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Canagliflozin — C24H25FO5S; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Canagliflozin — 444.5170 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Canagliflozin — Small molecule; Sildenafil — Small molecule.