Captopril vs Donepezil

## Captopril vs Donepezil: Overview

This comparison examines the pharmacological differences between **Captopril** and **Donepezil**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Donepezil**: Reversible acetylcholinesterase inhibitor.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Donepezil — 70 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Donepezil — C24H29NO3.

**Molecular Weight**: Captopril — 217.2850 g/mol; Donepezil — 379.4920 g/mol.

**Type**: Captopril — Small molecule; Donepezil — Small molecule.