Captopril vs Prednisone

## Captopril vs Prednisone: Overview

This comparison examines the pharmacological differences between **Captopril** and **Prednisone**.

## Mechanism of Action

**Captopril**: First orally active ACE inhibitor; contains thiol group that binds zinc at ACE active site.

**Prednisone**: Synthetic corticosteroid; suppresses inflammation via glucocorticoid receptor.

## Pharmacokinetics

**Half-life**: Captopril — 1.9 hours; Prednisone — 2-3 hours.

## Chemical Properties

**Molecular Formula**: Captopril — C9H15NO3S; Prednisone — C21H26O5.

**Molecular Weight**: Captopril — 217.2850 g/mol; Prednisone — 358.4280 g/mol.

**Type**: Captopril — Small molecule; Prednisone — Small molecule.