Citalopram vs Rituximab

## Citalopram vs Rituximab: Overview

This comparison examines the pharmacological differences between **Citalopram** and **Rituximab**.

## Mechanism of Action

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

**Rituximab**: Chimeric anti-CD20 IgG1 monoclonal antibody inducing B-cell depletion via CDC, ADCC, and apoptosis.

## Pharmacokinetics

**Half-life**: Citalopram — 35 hours; Rituximab — 22 days.

## Chemical Properties

**Molecular Formula**: Citalopram — C20H21FN2O; Rituximab — N/A.

**Molecular Weight**: Citalopram — 324.3920 g/mol; Rituximab — N/A.

**Type**: Citalopram — Small molecule; Rituximab — Antibody.