Citalopram vs Tofacitinib

## Citalopram vs Tofacitinib: Overview

This comparison examines the pharmacological differences between **Citalopram** and **Tofacitinib**.

## Mechanism of Action

**Citalopram**: Selective serotonin reuptake inhibitor (SSRI); racemic mixture with escitalopram as active S-enantiomer.

**Tofacitinib**: Pan-JAK inhibitor with preference for JAK1 and JAK3 blocking pro-inflammatory cytokine signaling.

## Pharmacokinetics

**Half-life**: Citalopram — 35 hours; Tofacitinib — 3.2 hours.

## Chemical Properties

**Molecular Formula**: Citalopram — C20H21FN2O; Tofacitinib — C16H20N6O.

**Molecular Weight**: Citalopram — 324.3920 g/mol; Tofacitinib — 312.3700 g/mol.

**Type**: Citalopram — Small molecule; Tofacitinib — Small molecule.