Dapagliflozin vs Upadacitinib

## Dapagliflozin vs Upadacitinib: Overview

This comparison examines the pharmacological differences between **Dapagliflozin** and **Upadacitinib**.

## Mechanism of Action

**Dapagliflozin**: Selective SGLT2 inhibitor reducing renal glucose and sodium reabsorption.

**Upadacitinib**: Selective JAK1 inhibitor reducing signaling from cytokines implicated in autoimmune diseases.

## Pharmacokinetics

**Half-life**: Dapagliflozin — 12.9 hours; Upadacitinib — 9-14 hours.

## Chemical Properties

**Molecular Formula**: Dapagliflozin — C21H25ClO6; Upadacitinib — C17H19F3N6O.

**Molecular Weight**: Dapagliflozin — 408.8730 g/mol; Upadacitinib — 380.3700 g/mol.

**Type**: Dapagliflozin — Small molecule; Upadacitinib — Small molecule.