Digoxin vs Tacrolimus

## Digoxin vs Tacrolimus: Overview

This comparison examines the pharmacological differences between **Digoxin** and **Tacrolimus**.

## Mechanism of Action

**Digoxin**: Inhibits Na+/K+-ATPase, increasing intracellular calcium.

**Tacrolimus**: Calcineurin inhibitor binding FKBP12; suppresses IL-2 transcription.

## Pharmacokinetics

**Half-life**: Digoxin — 36-48 hours; Tacrolimus — 12 hours.

## Chemical Properties

**Molecular Formula**: Digoxin — C41H64O14; Tacrolimus — C44H69NO12.

**Molecular Weight**: Digoxin — 780.9430 g/mol; Tacrolimus — 804.0180 g/mol.

**Type**: Digoxin — Small molecule; Tacrolimus — Small molecule.