Doxycycline vs Hydrochlorothiazide

## Doxycycline vs Hydrochlorothiazide: Overview

This comparison examines the pharmacological differences between **Doxycycline** and **Hydrochlorothiazide**.

## Mechanism of Action

**Doxycycline**: Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

## Pharmacokinetics

**Half-life**: Doxycycline — 18-22 hours; Hydrochlorothiazide — 6-15 hours.

## Chemical Properties

**Molecular Formula**: Doxycycline — C22H24N2O8; Hydrochlorothiazide — C7H8ClN3O4S2.

**Molecular Weight**: Doxycycline — 444.4350 g/mol; Hydrochlorothiazide — 297.7400 g/mol.

**Type**: Doxycycline — Small molecule; Hydrochlorothiazide — Small molecule.