Doxycycline vs Methotrexate

## Doxycycline vs Methotrexate: Overview

This comparison examines the pharmacological differences between **Doxycycline** and **Methotrexate**.

## Mechanism of Action

**Doxycycline**: Inhibits bacterial protein synthesis by binding 30S ribosomal subunit.

**Methotrexate**: Dihydrofolate reductase inhibitor.

## Pharmacokinetics

**Half-life**: Doxycycline — 18-22 hours; Methotrexate — 3-10 hours.

## Chemical Properties

**Molecular Formula**: Doxycycline — C22H24N2O8; Methotrexate — C20H22N8O5.

**Molecular Weight**: Doxycycline — 444.4350 g/mol; Methotrexate — 454.4400 g/mol.

**Type**: Doxycycline — Small molecule; Methotrexate — Small molecule.