Durvalumab vs Metformin

## Durvalumab vs Metformin: Overview

This comparison examines the pharmacological differences between **Durvalumab** and **Metformin**.

## Mechanism of Action

**Durvalumab**: Human IgG1 kappa anti-PD-L1 monoclonal antibody blocking PD-L1 binding to PD-1 and CD80.

**Metformin**: Activates AMP-activated protein kinase, decreasing hepatic glucose production.

## Pharmacokinetics

**Half-life**: Durvalumab — 17 days; Metformin — 4-9 hours.

## Chemical Properties

**Molecular Formula**: Durvalumab — N/A; Metformin — C4H11N5.

**Molecular Weight**: Durvalumab — N/A; Metformin — 129.1640 g/mol.

**Type**: Durvalumab — Antibody; Metformin — Small molecule.