Erlotinib vs Ipilimumab

## Erlotinib vs Ipilimumab: Overview

This comparison examines the pharmacological differences between **Erlotinib** and **Ipilimumab**.

## Mechanism of Action

**Erlotinib**: Reversible inhibitor of EGFR (HER1) tyrosine kinase, blocking autophosphorylation.

**Ipilimumab**: Fully human anti-CTLA-4 IgG1 monoclonal antibody that blocks CTLA-4 inhibitory signaling.

## Pharmacokinetics

**Half-life**: Erlotinib — 36 hours; Ipilimumab — 14.7 days.

## Chemical Properties

**Molecular Formula**: Erlotinib — C22H23N3O4; Ipilimumab — N/A.

**Molecular Weight**: Erlotinib — 393.4380 g/mol; Ipilimumab — N/A.

**Type**: Erlotinib — Small molecule; Ipilimumab — Antibody.