Erlotinib vs Sitagliptin

## Erlotinib vs Sitagliptin: Overview

This comparison examines the pharmacological differences between **Erlotinib** and **Sitagliptin**.

## Mechanism of Action

**Erlotinib**: Reversible inhibitor of EGFR (HER1) tyrosine kinase, blocking autophosphorylation.

**Sitagliptin**: DPP-4 inhibitor increasing incretin levels.

## Pharmacokinetics

**Half-life**: Erlotinib — 36 hours; Sitagliptin — 12.4 hours.

## Chemical Properties

**Molecular Formula**: Erlotinib — C22H23N3O4; Sitagliptin — C16H15F6N5O.

**Molecular Weight**: Erlotinib — 393.4380 g/mol; Sitagliptin — 407.3140 g/mol.

**Type**: Erlotinib — Small molecule; Sitagliptin — Small molecule.