Erlotinib vs Trastuzumab

## Erlotinib vs Trastuzumab: Overview

This comparison examines the pharmacological differences between **Erlotinib** and **Trastuzumab**.

## Mechanism of Action

**Erlotinib**: Reversible inhibitor of EGFR (HER1) tyrosine kinase, blocking autophosphorylation.

**Trastuzumab**: Anti-HER2 monoclonal antibody inhibiting receptor signaling.

## Pharmacokinetics

**Half-life**: Erlotinib — 36 hours; Trastuzumab — 28 days.

## Chemical Properties

**Molecular Formula**: Erlotinib — C22H23N3O4; Trastuzumab — N/A.

**Molecular Weight**: Erlotinib — 393.4380 g/mol; Trastuzumab — N/A.

**Type**: Erlotinib — Small molecule; Trastuzumab — Antibody.