Hydrochlorothiazide vs Memantine

## Hydrochlorothiazide vs Memantine: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Memantine**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Memantine**: Non-competitive NMDA receptor antagonist.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Memantine — 60-80 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Memantine — C12H21N.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Memantine — 179.3080 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Memantine — Small molecule.