Hydrochlorothiazide vs Omeprazole

## Hydrochlorothiazide vs Omeprazole: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Omeprazole**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Omeprazole**: Proton pump inhibitor that irreversibly blocks H+/K+-ATPase.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Omeprazole — 0.5-1 hour.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Omeprazole — C17H19N3O3S.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Omeprazole — 345.4170 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Omeprazole — Small molecule.