Hydrochlorothiazide vs Phenytoin

## Hydrochlorothiazide vs Phenytoin: Overview

This comparison examines the pharmacological differences between **Hydrochlorothiazide** and **Phenytoin**.

## Mechanism of Action

**Hydrochlorothiazide**: Inhibits Na+/Cl- cotransporter in distal convoluted tubule.

**Phenytoin**: Sodium channel blocker stabilizing inactive state.

## Pharmacokinetics

**Half-life**: Hydrochlorothiazide — 6-15 hours; Phenytoin — 22 hours.

## Chemical Properties

**Molecular Formula**: Hydrochlorothiazide — C7H8ClN3O4S2; Phenytoin — C15H12N2O2.

**Molecular Weight**: Hydrochlorothiazide — 297.7400 g/mol; Phenytoin — 252.2680 g/mol.

**Type**: Hydrochlorothiazide — Small molecule; Phenytoin — Small molecule.