Lorazepam vs Sertraline

## Lorazepam vs Sertraline: Overview

This comparison examines the pharmacological differences between **Lorazepam** and **Sertraline**.

## Mechanism of Action

**Lorazepam**: Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.

**Sertraline**: Selective serotonin reuptake inhibitor (SSRI).

## Pharmacokinetics

**Half-life**: Lorazepam — 10-20 hours; Sertraline — 26 hours.

## Chemical Properties

**Molecular Formula**: Lorazepam — C15H10Cl2N2O2; Sertraline — C17H17Cl2N.

**Molecular Weight**: Lorazepam — 321.1580 g/mol; Sertraline — 306.2290 g/mol.

**Type**: Lorazepam — Small molecule; Sertraline — Small molecule.