Losartan vs Spironolactone

## Losartan vs Spironolactone: Overview

This comparison examines the pharmacological differences between **Losartan** and **Spironolactone**.

## Mechanism of Action

**Losartan**: Angiotensin II receptor type 1 antagonist.

**Spironolactone**: Mineralocorticoid receptor antagonist.

## Pharmacokinetics

**Half-life**: Losartan — 2 hours; Spironolactone — 1.4 hours.

## Chemical Properties

**Molecular Formula**: Losartan — C22H23ClN6O; Spironolactone — C24H32O4S.

**Molecular Weight**: Losartan — 422.9200 g/mol; Spironolactone — 416.5740 g/mol.

**Type**: Losartan — Small molecule; Spironolactone — Small molecule.