Moxifloxacin vs Trimethoprim

## Moxifloxacin vs Trimethoprim: Overview

This comparison examines the pharmacological differences between **Moxifloxacin** and **Trimethoprim**.

## Mechanism of Action

**Moxifloxacin**: Fourth-generation fluoroquinolone inhibiting DNA gyrase and topoisomerase IV with enhanced anaerobic activity.

**Trimethoprim**: Dihydrofolate reductase inhibitor (bacterial selective).

## Pharmacokinetics

**Half-life**: Moxifloxacin — 12 hours; Trimethoprim — 8-10 hours.

## Chemical Properties

**Molecular Formula**: Moxifloxacin — C21H24FN3O4; Trimethoprim — C14H18N4O3.

**Molecular Weight**: Moxifloxacin — 401.4350 g/mol; Trimethoprim — 290.3180 g/mol.

**Type**: Moxifloxacin — Small molecule; Trimethoprim — Small molecule.