Naproxen vs Sildenafil

## Naproxen vs Sildenafil: Overview

This comparison examines the pharmacological differences between **Naproxen** and **Sildenafil**.

## Mechanism of Action

**Naproxen**: Non-selective COX inhibitor.

**Sildenafil**: Selective PDE5 inhibitor increasing cGMP.

## Pharmacokinetics

**Half-life**: Naproxen — 12-17 hours; Sildenafil — 4 hours.

## Chemical Properties

**Molecular Formula**: Naproxen — C14H14O3; Sildenafil — C22H30N6O4S.

**Molecular Weight**: Naproxen — 230.2590 g/mol; Sildenafil — 474.5800 g/mol.

**Type**: Naproxen — Small molecule; Sildenafil — Small molecule.