Norfloxacin vs Vancomycin

## Norfloxacin vs Vancomycin: Overview

This comparison examines the pharmacological differences between **Norfloxacin** and **Vancomycin**.

## Mechanism of Action

**Norfloxacin**: Second-generation fluoroquinolone inhibiting bacterial DNA gyrase and topoisomerase IV.

**Vancomycin**: Glycopeptide antibiotic inhibiting cell wall synthesis by binding D-Ala-D-Ala terminus of peptidoglycan precursors.

## Pharmacokinetics

**Half-life**: Norfloxacin — 3-4 hours; Vancomycin — 4-6 hours.

## Chemical Properties

**Molecular Formula**: Norfloxacin — C16H18FN3O3; Vancomycin — C66H75Cl2N9O24.

**Molecular Weight**: Norfloxacin — 319.3310 g/mol; Vancomycin — 1449.2500 g/mol.

**Type**: Norfloxacin — Small molecule; Vancomycin — Small molecule.