Phenytoin vs Pregabalin

## Phenytoin vs Pregabalin: Overview

This comparison examines the pharmacological differences between **Phenytoin** and **Pregabalin**.

## Mechanism of Action

**Phenytoin**: Sodium channel blocker stabilizing inactive state.

**Pregabalin**: Binds alpha-2-delta subunit of voltage-gated calcium channels.

## Pharmacokinetics

**Half-life**: Phenytoin — 22 hours; Pregabalin — 6.3 hours.

## Chemical Properties

**Molecular Formula**: Phenytoin — C15H12N2O2; Pregabalin — C8H17NO2.

**Molecular Weight**: Phenytoin — 252.2680 g/mol; Pregabalin — 159.2260 g/mol.

**Type**: Phenytoin — Small molecule; Pregabalin — Small molecule.