Sertraline vs Upadacitinib

## Sertraline vs Upadacitinib: Overview

This comparison examines the pharmacological differences between **Sertraline** and **Upadacitinib**.

## Mechanism of Action

**Sertraline**: Selective serotonin reuptake inhibitor (SSRI).

**Upadacitinib**: Selective JAK1 inhibitor reducing signaling from cytokines implicated in autoimmune diseases.

## Pharmacokinetics

**Half-life**: Sertraline — 26 hours; Upadacitinib — 9-14 hours.

## Chemical Properties

**Molecular Formula**: Sertraline — C17H17Cl2N; Upadacitinib — C17H19F3N6O.

**Molecular Weight**: Sertraline — 306.2290 g/mol; Upadacitinib — 380.3700 g/mol.

**Type**: Sertraline — Small molecule; Upadacitinib — Small molecule.