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Acitretin

CHEMBL1131 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
326.4 g/mol
LogP
6.1
Phase
4

An oral retinoid medication derived from vitamin A that is used to treat severe psoriasis and other serious skin disorders by regulating abnormal skin cell growth and reducing inflammation. It is highly effective for pustular and erythrodermic psoriasis but requires strict pregnancy prevention because it causes severe birth defects; women must avoid pregnancy for three years after stopping treatment. Regular blood tests to monitor liver function and blood lipid levels are essential during therapy.

आणविक भार

326.4000 g/mol

LogP

6.10

TPSA

46.50 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

एटोपिक डर्मेटाइटिस (एक्जिमा) मेलानोमा सोरायसिस हाइपरलिपिडेमिया

क्रिया का तंत्र

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1cc(C)c(/C=C/C(C)=C/C=C/C(C)=C/C(=O)O)c(C)c1C

                

                

                
                

                    
InChI

                    
InChI=1S/C21H26O3/c1-14(8-7-9-15(2)12-21(22)23)10-11-19-16(3)13-20(24-6)18(5)17(19)4/h7-13H,1-6H3,(H,22,23)/b9-7+,11-10+,14-8+,15-12+

                

                

                

                    
                    

                        
Molecular Formula

                        
C21H26O3

                    

                    
                    

                        
HBD / HBA

                        
1 / 3

                    

                    
                    

                        
घूर्णनीय बंधन

                        
6

                    

                    
                    
                    

                        
भारी परमाणु

                        
24

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
An oral retinoid medication derived from vitamin A that is used to treat severe psoriasis and other serious skin disorders by regulating abnormal skin cell growth and reducing inflammation. It is highly effective for pustular and erythrodermic psoriasis but requires strict pregnancy prevention because it causes severe birth defects; women must avoid pregnancy for three years after stopping treatment. Regular blood tests to monitor liver function and blood lipid levels are essential during therapy.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Serves as an essential micronutrient cofactor in various enzymatic reactions and metabolic processes. Supplementation corrects deficiency states and supports normal physiological function.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Acitretin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1131.
                Open-access bioactivity database.
            
        
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  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5284513.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.