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Amenamevir

CHEMBL4297592 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
482.6 g/mol
LogP
2.6
Phase
4

An antiviral medication that inhibits the helicase-primase enzyme complex essential for herpesvirus DNA replication, offering a different mechanism of action from nucleoside analogues like acyclovir. It is approved in Japan for treating herpes zoster (shingles) and may be effective in patients with acyclovir-resistant herpesvirus infections.

आणविक भार

482.6000 g/mol

LogP

2.60

TPSA

131.00 Ų

लिपिंस्की RO5

उत्तीर्ण

क्रिया का तंत्र

Incorporated into viral DNA by reverse transcriptase as a nucleoside analog, causing chain termination and inhibition of viral replication.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Incorporated into viral DNA by reverse transcriptase as a nucleoside analog, causing chain termination and inhibition of viral replication.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
Cc1cccc(C)c1N(CC(=O)Nc1ccc(-c2ncon2)cc1)C(=O)C1CCS(=O)(=O)CC1

                

                

                
                

                    
InChI

                    
InChI=1S/C24H26N4O5S/c1-16-4-3-5-17(2)22(16)28(24(30)19-10-12-34(31,32)13-11-19)14-21(29)26-20-8-6-18(7-9-20)23-25-15-33-27-23/h3-9,15,19H,10-14H2,1-2H3,(H,26,29)

                

                

                

                    
                    

                        
Molecular Formula

                        
C24H26N4O5S

                    

                    
                    

                        
HBD / HBA

                        
1 / 7

                    

                    
                    

                        
घूर्णनीय बंधन

                        
6

                    

                    
                    
                    

                        
भारी परमाणु

                        
34

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
An antiviral medication that inhibits the helicase-primase enzyme complex essential for herpesvirus DNA replication, offering a different mechanism of action from nucleoside analogues like acyclovir. It is approved in Japan for treating herpes zoster (shingles) and may be effective in patients with acyclovir-resistant herpesvirus infections.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Incorporated into viral DNA by reverse transcriptase as a nucleoside analog, causing chain termination and inhibition of viral replication.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Amenamevir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL4297592.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 11397521.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.