Amprenavir
A protease inhibitor that blocks an enzyme HIV needs to produce infectious new virus particles, reducing the amount of virus in the blood. It was an early option in combination HIV therapy, though it has largely been replaced by newer agents.
आणविक भार
505.6000 g/mol
LogP
2.90
TPSA
140.00 Ų
लिपिंस्की RO5
उत्तीर्ण
चिकित्सीय क्षेत्र
क्रिया का तंत्र
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
2D संरचना
Cite this structure
Embed this structure
SMILES
CC(C)CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)O[C@H]1CCOC1)S(=O)(=O)c1ccc(N)cc1
InChI
InChI=1S/C25H35N3O6S/c1-18(2)15-28(35(31,32)22-10-8-20(26)9-11-22)16-24(29)23(14-19-6-4-3-5-7-19)27-25(30)34-21-12-13-33-17-21/h3-11,18,21,23-24,29H,12-17,26H2,1-2H3,(H,27,30)/t21-,23-,24+/m0/s1
Molecular Formula
C25H35N3O6S
HBD / HBA
3 / 8
घूर्णनीय बंधन
12
भारी परमाणु
35
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
A protease inhibitor that blocks an enzyme HIV needs to produce infectious new virus particles, reducing the amount of virus in the blood. It was an early option in combination HIV therapy, though it has largely been replaced by newer agents.
Inhibits viral protease, an enzyme essential for cleaving polyprotein precursors into functional viral proteins required for viral maturation and infectivity.
Yes, Amprenavir is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL116. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 65016. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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