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Bepridil

CHEMBL1008 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
366.5 g/mol
LogP
5.3
Phase
4

A calcium channel blocker that was used to treat chronic stable angina and certain heart arrhythmias. It works by slowing electrical conduction in the heart and relaxing blood vessels. Due to serious cardiac side effects, including potentially fatal arrhythmias, its use was discontinued in many countries.

आणविक भार

366.5000 g/mol

LogP

5.30

TPSA

15.70 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

Stroke Hypertension

क्रिया का तंत्र

Blocks L-type voltage-gated calcium channels in vascular smooth muscle and cardiac myocytes, reducing calcium influx during depolarization. This produces vasodilation, decreased myocardial contractility, and reduced heart rate.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Blocks L-type voltage-gated calcium channels in vascular smooth muscle and cardiac myocytes, reducing calcium influx during depolarization. This produces vasodilation, decreased myocardial contractility, and reduced heart rate.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1

                

                

                
                

                    
InChI

                    
InChI=1S/C24H34N2O/c1-21(2)19-27-20-24(25-15-9-10-16-25)18-26(23-13-7-4-8-14-23)17-22-11-5-3-6-12-22/h3-8,11-14,21,24H,9-10,15-20H2,1-2H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C24H34N2O

                    

                    
                    

                        
HBD / HBA

                        
- / 3

                    

                    
                    

                        
घूर्णनीय बंधन

                        
10

                    

                    
                    
                    

                        
भारी परमाणु

                        
27

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
A calcium channel blocker that was used to treat chronic stable angina and certain heart arrhythmias. It works by slowing electrical conduction in the heart and relaxing blood vessels. Due to serious cardiac side effects, including potentially fatal arrhythmias, its use was discontinued in many countries.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Blocks L-type voltage-gated calcium channels in vascular smooth muscle and cardiac myocytes, reducing calcium influx during depolarization. This produces vasodilation, decreased myocardial contractility, and reduced heart rate.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Bepridil is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1008.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2351.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.