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Betamethasone

CHEMBL632 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
392.5 g/mol
LogP
1.9
Phase
4

A potent synthetic corticosteroid that reduces inflammation and suppresses the immune system, used to treat a wide range of conditions including severe allergies, skin disorders, and inflammatory diseases. It is available in many formulations including creams, injections, and tablets. Long-term use carries risks of adrenal suppression and other systemic effects.

आणविक भार

392.5000 g/mol

LogP

1.90

TPSA

94.80 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

अस्थमा एटोपिक डर्मेटाइटिस (एक्जिमा) ऑस्टियोपोरोसिस कोलोरेक्टल कैंसर गाउट (गठिया) ग्लूकोमा दर्द प्रबंधन दीर्घकालिक दर्द माइग्रेन मेलानोमा रुमेटॉइड आर्थराइटिस सिस्टेमिक ल्यूपस एरिथेमेटोसस सोरायसिस स्ट्रोक स्तन कैंसर हेपेटाइटिस C

क्रिया का तंत्र

Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO

                

                

                
                

                    
InChI

                    
InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C22H29FO5

                    

                    
                    

                        
HBD / HBA

                        
3 / 6

                    

                    
                    

                        
घूर्णनीय बंधन

                        
2

                    

                    
                    
                    

                        
भारी परमाणु

                        
28

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
A potent synthetic corticosteroid that reduces inflammation and suppresses the immune system, used to treat a wide range of conditions including severe allergies, skin disorders, and inflammatory diseases. It is available in many formulations including creams, injections, and tablets. Long-term use carries risks of adrenal suppression and other systemic effects.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Binds to intracellular glucocorticoid receptors, translocating to the nucleus to modulate gene transcription. This suppresses multiple inflammatory genes encoding cytokines, chemokines, and adhesion molecules while inducing anti-inflammatory proteins.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Betamethasone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL632.
                Open-access bioactivity database.
            
        
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  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 9782.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.