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Broxyquinoline

CHEMBL223448 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
303.0 g/mol
LogP
3.2
Phase
4

An antimicrobial compound with activity against bacteria, fungi, and protozoa, used historically as an intestinal antiseptic for traveler's diarrhea and intestinal infections. It is a halogenated hydroxyquinoline derivative. Its use has declined due to safety concerns seen with related compounds in the same chemical class.

आणविक भार

302.9500 g/mol

LogP

3.20

TPSA

33.10 Ų

लिपिंस्की RO5

उत्तीर्ण

क्रिया का तंत्र

Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
Oc1c(Br)cc(Br)c2cccnc12

                

                

                
                

                    
InChI

                    
InChI=1S/C9H5Br2NO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H

                

                

                

                    
                    

                        
Molecular Formula

                        
C9H5Br2NO

                    

                    
                    

                        
HBD / HBA

                        
1 / 2

                    

                    
                    

                        
घूर्णनीय बंधन

                        
0

                    

                    
                    
                    

                        
भारी परमाणु

                        
13

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
An antimicrobial compound with activity against bacteria, fungi, and protozoa, used historically as an intestinal antiseptic for traveler's diarrhea and intestinal infections. It is a halogenated hydroxyquinoline derivative. Its use has declined due to safety concerns seen with related compounds in the same chemical class.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Disrupts microbial cell membranes and denatures proteins on contact, producing rapid broad-spectrum antimicrobial activity on skin and wound surfaces.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Broxyquinoline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL223448.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 2453.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.