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Cevimeline

CHEMBL168815 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
199.3 g/mol
LogP
1.5
Phase
4

A cholinergic agonist that stimulates muscarinic M3 receptors in exocrine glands, increasing saliva and tear production. It is indicated for the treatment of dry mouth in patients with Sjögren's syndrome. Common side effects reflect its muscarinic stimulation and include sweating, nausea, and urinary frequency.

आणविक भार

199.3200 g/mol

LogP

1.50

TPSA

37.80 Ų

लिपिंस्की RO5

उत्तीर्ण

क्रिया का तंत्र

Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CC1OC2(CS1)CN1CCC2CC1

                

                

                
                

                    
InChI

                    
InChI=1S/C10H17NOS/c1-8-12-10(7-13-8)6-11-4-2-9(10)3-5-11/h8-9H,2-7H2,1H3

                

                

                

                    
                    

                        
Molecular Formula

                        
C10H17NOS

                    

                    
                    

                        
HBD / HBA

                        
- / 3

                    

                    
                    

                        
घूर्णनीय बंधन

                        
0

                    

                    
                    
                    

                        
भारी परमाणु

                        
13

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
A cholinergic agonist that stimulates muscarinic M3 receptors in exocrine glands, increasing saliva and tear production. It is indicated for the treatment of dry mouth in patients with Sjögren's syndrome. Common side effects reflect its muscarinic stimulation and include sweating, nausea, and urinary frequency.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Competitively blocks muscarinic acetylcholine receptors, reducing parasympathetic nervous system activity. Effects include decreased secretions, bronchodilation, and relaxation of smooth muscle.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Cevimeline is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL168815.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 25137844.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.