Duvelisib
A dual PI3K delta and gamma inhibitor used to treat chronic lymphocytic leukemia and follicular lymphoma in patients who have received prior therapy. It blocks signaling pathways that allow cancer cells to survive and proliferate.
आणविक भार
416.9000 g/mol
LogP
4.10
TPSA
86.80 Ų
लिपिंस्की RO5
उत्तीर्ण
चिकित्सीय क्षेत्र
Pharmacokinetics (PK)
Pharmacodynamics (PD)
2D संरचना
Cite this structure
Embed this structure
SMILES
C[C@H](Nc1ncnc2nc[nH]c12)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1
InChI
InChI=1S/C22H17ClN6O/c1-13(28-21-19-20(25-11-24-19)26-12-27-21)17-10-14-6-5-9-16(23)18(14)22(30)29(17)15-7-3-2-4-8-15/h2-13H,1H3,(H2,24,25,26,27,28)/t13-/m0/s1
Molecular Formula
C22H17ClN6O
HBD / HBA
2 / 5
घूर्णनीय बंधन
4
भारी परमाणु
30
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
A dual PI3K delta and gamma inhibitor used to treat chronic lymphocytic leukemia and follicular lymphoma in patients who have received prior therapy. It blocks signaling pathways that allow cancer cells to survive and proliferate.
Yes, Duvelisib is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL3039502. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 50905713. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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