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Elapegademase

CHEMBL3990026 Phase 4 अनुमोदित Enzyme
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
248.3 g/mol
LogP
-2.7
Phase
4

This enzyme replacement therapy provides a working version of adenosine deaminase, an enzyme missing in a rare form of severe combined immunodeficiency. Regular injections help restore immune system function in affected patients.

आणविक भार

248.2800 g/mol

LogP

-2.70

TPSA

111.00 Ų

लिपिंस्की RO5

उत्तीर्ण

क्रिया का तंत्र

Provides exogenous replacement of the deficient or absent enzyme, enabling the metabolic processing of accumulated substrates and restoring normal metabolic function.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Provides exogenous replacement of the deficient or absent enzyme, enabling the metabolic processing of accumulated substrates and restoring normal metabolic function.

2D संरचना

SVG PNG

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SMILES

                    
COCCOC(=O)NCCCC[C@@H](C(=O)O)N

                

                

                
                

                    
InChI

                    
InChI=1S/C10H20N2O5/c1-16-6-7-17-10(15)12-5-3-2-4-8(11)9(13)14/h8H,2-7,11H2,1H3,(H,12,15)(H,13,14)/t8-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C10H20N2O5

                    

                    
                    

                        
HBD / HBA

                        
3 / 6

                    

                    
                    

                        
घूर्णनीय बंधन

                        
10

                    

                    
                    
                    

                        
भारी परमाणु

                        
17

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
This enzyme replacement therapy provides a working version of adenosine deaminase, an enzyme missing in a rare form of severe combined immunodeficiency. Regular injections help restore immune system function in affected patients.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Provides exogenous replacement of the deficient or absent enzyme, enabling the metabolic processing of accumulated substrates and restoring normal metabolic function.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Elapegademase is an approved drug. It has reached clinical phase 4. It is classified as a Enzyme.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL3990026.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 121488177.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.