Enalapril
This medication relaxes blood vessels by blocking an enzyme that produces a hormone called angiotensin II, making it easier for the heart to pump blood. It is widely used to treat high blood pressure and heart failure.
आणविक भार
376.4470 g/mol
LogP
-0.10
TPSA
95.90 Ų
लिपिंस्की RO5
उत्तीर्ण
चिकित्सीय क्षेत्र
दवा वर्ग
क्रिया का तंत्र
Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.
2D संरचना
Cite this structure
Embed this structure
SMILES
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(=O)O
InChI
InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
Molecular Formula
C20H28N2O5
HBD / HBA
2 / 6
घूर्णनीय बंधन
10
भारी परमाणु
27
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
This medication relaxes blood vessels by blocking an enzyme that produces a hormone called angiotensin II, making it easier for the heart to pump blood. It is widely used to treat high blood pressure and heart failure.
Prodrug converted to enalaprilat; inhibits ACE preventing angiotensin I to II conversion.
Key pharmacokinetic parameters for Enalapril: Half-life: 11 hours.
Yes, Enalapril is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL578. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 5388962. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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