Enmetazobactam

CHEMBL4458276 Phase 4 अनुमोदित Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

314.3 g/mol

LogP

-0.6

Phase

4

This medication protects certain antibiotics from being broken down by bacterial enzymes called beta-lactamases, allowing the antibiotic to work effectively. It is given in combination with an antibiotic to treat resistant bacterial infections.

आणविक भार

314.3200 g/mol

LogP

-0.60

TPSA

125.00 Å²

लिपिंस्की RO5

उत्तीर्ण

क्रिया का तंत्र

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell death.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell …

2D संरचना

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SMILES

C[n+]1ccn(C[C@@]2(C)[C@H](C(=O)[O-])N3C(=O)C[C@H]3S2(=O)=O)n1

InChI

InChI=1S/C11H14N4O5S/c1-11(6-14-4-3-13(2)12-14)9(10(17)18)15-7(16)5-8(15)21(11,19)20/h3-4,8-9H,5-6H2,1-2H3/t8-,9+,11+/m1/s1

Molecular Formula

C11H14N4O5S

HBD / HBA

- / 6

घूर्णनीय बंधन

2

भारी परमाणु

21

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

This medication protects certain antibiotics from being broken down by bacterial enzymes called beta-lactamases, allowing the antibiotic to work effectively. It is given in combination with an antibiotic to treat resistant bacterial infections.

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), preventing transpeptidation and cross-linking of peptidoglycan chains. This weakens the bacterial cell wall, leading to osmotic lysis and cell death.

Yes, Enmetazobactam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL4458276. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 23653540. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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संरचना

त्वरित डेटा

सूत्र: C11H14N4O5S

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चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.