Ethacrynic Acid
This loop diuretic works by blocking salt reabsorption in the kidneys, causing the body to excrete more sodium and water in the urine. It is used to treat fluid overload in conditions such as heart failure and kidney disease.
आणविक भार
303.1300 g/mol
LogP
3.80
TPSA
63.60 Ų
लिपिंस्की RO5
उत्तीर्ण
चिकित्सीय क्षेत्र
क्रिया का तंत्र
Inhibits sodium reabsorption in the renal tubules, promoting excretion of sodium, chloride, and water. This reduces extracellular fluid volume and cardiac preload, lowering blood pressure.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Inhibits sodium reabsorption in the renal tubules, promoting excretion of sodium, chloride, and water. This reduces extracellular fluid volume and cardiac preload, lowering blood pressure.
2D संरचना
Cite this structure
Embed this structure
SMILES
C=C(CC)C(=O)c1ccc(OCC(=O)O)c(Cl)c1Cl
InChI
InChI=1S/C13H12Cl2O4/c1-3-7(2)13(18)8-4-5-9(12(15)11(8)14)19-6-10(16)17/h4-5H,2-3,6H2,1H3,(H,16,17)
Molecular Formula
C13H12Cl2O4
HBD / HBA
1 / 4
घूर्णनीय बंधन
6
भारी परमाणु
19
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
This loop diuretic works by blocking salt reabsorption in the kidneys, causing the body to excrete more sodium and water in the urine. It is used to treat fluid overload in conditions such as heart failure and kidney disease.
Inhibits sodium reabsorption in the renal tubules, promoting excretion of sodium, chloride, and water. This reduces extracellular fluid volume and cardiac preload, lowering blood pressure.
Yes, Ethacrynic Acid is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL456. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3278. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
Embed This Widget
Add the script tag and a data attribute to embed this widget.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<div data-drugfyi="drug" data-slug="ethacrynic-acid"></div>
Embed via iframe for maximum compatibility.
<iframe src="https://drugfyi.com/iframe/drug/ethacrynic-acid/" width="420" height="400" frameborder="0" style="border:0;border-radius:10px;max-width:100%" loading="lazy"></iframe>
Paste this URL in WordPress, Medium, or any oEmbed-compatible platform.
https://drugfyi.com/drug/ethacrynic-acid/
Add a dynamic SVG badge to your README or docs.
[](https://drugfyi.com/drug/ethacrynic-acid/)
Use the native HTML custom element.
<script src="https://cdn.jsdelivr.net/npm/drugfyi-embed@1/dist/embed.min.js" defer></script>
<drugfyi-drug slug="ethacrynic-acid"></drugfyi-drug>