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Fluvastatin

CHEMBL2220442 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
411.5 g/mol
LogP
3.5
Phase
4

This statin medication lowers LDL cholesterol and triglycerides by blocking the enzyme HMG-CoA reductase in the liver, which is responsible for cholesterol production. It reduces the risk of cardiovascular events in people with high cholesterol or established heart disease.

आणविक भार

411.5000 g/mol

LogP

3.50

TPSA

82.70 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

उच्च रक्तचाप ऑस्टियोपोरोसिस टाइप 2 मधुमेह प्रोस्टेट कैंसर मेलानोमा सिज़ोफ्रेनिया स्ट्रोक स्तन कैंसर हाइपरलिपिडेमिया हृदय-संवहनी रोग हेपेटाइटिस C

क्रिया का तंत्र

Competitively inhibits HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol biosynthesis. This reduces intracellular cholesterol, upregulates LDL receptor expression, and lowers circulating LDL cholesterol.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Competitively inhibits HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol biosynthesis. This reduces intracellular cholesterol, upregulates LDL receptor expression, and lowers circulating LDL cholesterol.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
CC(C)n1c(/C=C/C(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)c2ccccc21

                

                

                
                

                    
InChI

                    
InChI=1S/C24H26FNO4/c1-15(2)26-21-6-4-3-5-20(21)24(16-7-9-17(25)10-8-16)22(26)12-11-18(27)13-19(28)14-23(29)30/h3-12,15,18-19,27-28H,13-14H2,1-2H3,(H,29,30)/b12-11+

                

                

                

                    
                    

                        
Molecular Formula

                        
C24H26FNO4

                    

                    
                    

                        
HBD / HBA

                        
3 / 5

                    

                    
                    

                        
घूर्णनीय बंधन

                        
8

                    

                    
                    
                    

                        
भारी परमाणु

                        
30

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
This statin medication lowers LDL cholesterol and triglycerides by blocking the enzyme HMG-CoA reductase in the liver, which is responsible for cholesterol production. It reduces the risk of cardiovascular events in people with high cholesterol or established heart disease.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Competitively inhibits HMG-CoA reductase, the rate-limiting enzyme in the mevalonate pathway of cholesterol biosynthesis. This reduces intracellular cholesterol, upregulates LDL receptor expression, and lowers circulating LDL cholesterol.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Fluvastatin is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL2220442.
                Open-access bioactivity database.
            
        
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  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 1548972.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.