Golimumab

CHEMBL1201833 Phase 4 अनुमोदित Antibody
Half-Life
Bioavailability
Protein Binding
Molecular Weight
g/mol
LogP
Phase
4

A fully human monoclonal antibody that inhibits tumor necrosis factor-alpha, a key driver of inflammation in conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and inflammatory bowel disease. It is administered by subcutaneous injection monthly or intravenously for certain indications. Patients should be screened for tuberculosis and other infections before starting treatment.

चिकित्सीय क्षेत्र

क्रिया का तंत्र

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

HBD / HBA

- / -

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

A fully human monoclonal antibody that inhibits tumor necrosis factor-alpha, a key driver of inflammation in conditions such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and inflammatory bowel disease. It is administered by subcutaneous injection monthly or intravenously for certain indications. Patients should be screened for tuberculosis and other infections before starting treatment.

As a monoclonal antibody, it binds with high specificity to its target antigen, modulating the immune response through mechanisms including receptor blockade, immune cell engagement, or targeted cytotoxicity.

Yes, Golimumab is an approved drug. It has reached clinical phase 4. It is classified as a Antibody.

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References & Data Sources

  • ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1201833. Open-access bioactivity database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-02-27.

चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.