Hydralazine

CHEMBL276832 Phase 4 अनुमोदित Small molecule

Half-Life

—

Bioavailability

—

Protein Binding

—

Molecular Weight

160.2 g/mol

LogP

0.7

Phase

4

A direct-acting vasodilator that relaxes arterial smooth muscle to lower blood pressure, used to treat moderate to severe hypertension, heart failure, and hypertensive emergencies during pregnancy. It is often combined with other antihypertensives as it triggers reflex tachycardia and sodium retention when used alone. Research has explored its potential role in epigenetic regulation relevant to certain cancers.

आणविक भार

160.1800 g/mol

LogP

0.70

TPSA

63.80 Å²

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

उच्च रक्तचाप ओवेरियन कैंसर कोलोरेक्टल कैंसर टाइप 2 मधुमेह नॉन-स्मॉल सेल लंग कैंसर मिर्गी (एपिलेप्सी) स्ट्रोक स्तन कैंसर हृदय विफलता हृदय-संवहनी रोग

Pharmacokinetics (PK)

Pharmacodynamics (PD)

2D संरचना

SVG PNG

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SMILES

NNc1nncc2ccccc12

InChI

InChI=1S/C8H8N4/c9-11-8-7-4-2-1-3-6(7)5-10-12-8/h1-5H,9H2,(H,11,12)

Molecular Formula

C8H8N4

HBD / HBA

2 / 4

घूर्णनीय बंधन

1

भारी परमाणु

12

No targets recorded

Target interaction data is not yet available for this drug.

No interactions recorded

Drug interaction data is not yet available for this compound.

No side effects recorded

Side effect data is not yet available for this drug.

अक्सर पूछे जाने वाले प्रश्न

A direct-acting vasodilator that relaxes arterial smooth muscle to lower blood pressure, used to treat moderate to severe hypertension, heart failure, and hypertensive emergencies during pregnancy. It is often combined with other antihypertensives as it triggers reflex tachycardia and sodium retention when used alone. Research has explored its potential role in epigenetic regulation relevant to certain cancers.

Yes, Hydralazine is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

{# References & Data Sources section for drug detail pages. Renders standard pharmacological database links plus the drug's data_sources field. #}

References & Data Sources

ChEMBL — European Bioinformatics Institute (EBI). CHEMBL276832. Open-access bioactivity database.
PubChem — National Center for Biotechnology Information (NCBI). CID 3637. Chemical information database.

Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.

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संरचना

त्वरित डेटा

सूत्र: C8H8N4
पर्यायवाची: 3

बाहरी लिंक

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चिकित्सा अस्वीकरण

This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.

Data sources: ChEMBL, PubChem, DailyMed.