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Hydrocodone

CHEMBL1457 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
299.4 g/mol
LogP
2.2
Phase
4

An opioid pain reliever and cough suppressant used to treat moderate to severe pain and to suppress chronic cough, working by binding to opioid receptors in the brain and spinal cord to alter the perception of pain. It is typically formulated in combination with acetaminophen or other non-opioid analgesics. Due to its high potential for dependence and abuse, it is a Schedule II controlled substance requiring careful prescribing.

आणविक भार

299.4000 g/mol

LogP

2.20

TPSA

38.80 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

दर्द प्रबंधन दीर्घकालिक दर्द मोटापा लिम्फोमा स्तन कैंसर

क्रिया का तंत्र

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COc1ccc2c3c1O[C@H]1C(=O)CC[C@H]4[C@@H](C2)N(C)CC[C@]314

                

                

                
                

                    
InChI

                    
InChI=1S/C18H21NO3/c1-19-8-7-18-11-4-5-13(20)17(18)22-16-14(21-2)6-3-10(15(16)18)9-12(11)19/h3,6,11-12,17H,4-5,7-9H2,1-2H3/t11-,12+,17-,18-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C18H21NO3

                    

                    
                    

                        
HBD / HBA

                        
- / 4

                    

                    
                    

                        
घूर्णनीय बंधन

                        
1

                    

                    
                    
                    

                        
भारी परमाणु

                        
22

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
An opioid pain reliever and cough suppressant used to treat moderate to severe pain and to suppress chronic cough, working by binding to opioid receptors in the brain and spinal cord to alter the perception of pain. It is typically formulated in combination with acetaminophen or other non-opioid analgesics. Due to its high potential for dependence and abuse, it is a Schedule II controlled substance requiring careful prescribing.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Hydrocodone is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1457.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5284569.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.