💊 दवाएँ A-Z 🧬 लक्ष्य 🛠 उपकरण 📚 मार्गदर्शिकाएँ
सभी दवाएँ दवा वर्ग चिकित्सीय क्षेत्र दुष्प्रभाव
मार्गदर्शिकाएँ शब्दकोश समयरेखा
तुलनाएँ दवाओं की यात्राएँ दवा परिवार
🇺🇸 English 🇰🇷 한국어 🇯🇵 日本語 🇨🇳 中文简体 🇪🇸 Español 🇧🇷 Português 🇮🇳 हिन्दी 🇸🇦 العربية 🇫🇷 Français 🇷🇺 Русский 🇩🇪 Deutsch 🇹🇷 Türkçe 🇻🇳 Tiếng Việt 🇮🇩 Bahasa Indonesia 🇹🇭 ไทย

Hydrocortisone Valerate

CHEMBL1200562 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
446.6 g/mol
LogP
3.8
Phase
4

A valerate ester of hydrocortisone used as a moderate-potency topical corticosteroid for inflammatory skin conditions such as atopic dermatitis, psoriasis, and seborrheic dermatitis. The valerate ester increases skin penetration compared to plain hydrocortisone, providing more effective anti-inflammatory action at the site of application. It is available in cream and ointment forms for external application.

आणविक भार

446.6000 g/mol

LogP

3.80

TPSA

101.00 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

HIV/एड्स अग्नाशय कैंसर अनिद्रा अस्थमा इंफ्लेमेटरी बाउल डिज़ीज़ उच्च रक्तचाप एटोपिक डर्मेटाइटिस (एक्जिमा) एट्रियल फ़िब्रिलेशन ओवेरियन कैंसर कोलोरेक्टल कैंसर क्रॉनिक ऑब्सट्रक्टिव पल्मोनरी डिज़ीज़ (COPD) क्षय रोग (ट्यूबरकुलोसिस) गाउट (गठिया) ग्लूकोमा जनरलाइज़्ड एंग्ज़ाइटी डिसऑर्डर टाइप 2 मधुमेह थायरॉइड कैंसर दर्द प्रबंधन दीर्घकालिक दर्द नॉन-स्मॉल सेल लंग कैंसर पार्किंसन रोग प्रोस्टेट कैंसर बिनाइन प्रोस्टेटिक हाइपरप्लासिया मल्टीपल स्क्लेरोसिस मूत्राशय कैंसर मेजर डिप्रेसिव डिसऑर्डर मेलानोमा मोटापा रुमेटॉइड आर्थराइटिस लिम्फोमा ल्यूकेमिया सिस्टेमिक ल्यूपस एरिथेमेटोसस सोरायसिस स्ट्रोक स्तन कैंसर हृदय विफलता

क्रिया का तंत्र

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
CCCCC(=O)O[C@]1(C(=O)CO)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@@]21C

                

                

                
                

                    
InChI

                    
InChI=1S/C26H38O6/c1-4-5-6-22(31)32-26(21(30)15-27)12-10-19-18-8-7-16-13-17(28)9-11-24(16,2)23(18)20(29)14-25(19,26)3/h13,18-20,23,27,29H,4-12,14-15H2,1-3H3/t18-,19-,20-,23+,24-,25-,26-/m0/s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C26H38O6

                    

                    
                    

                        
HBD / HBA

                        
2 / 6

                    

                    
                    

                        
घूर्णनीय बंधन

                        
7

                    

                    
                    
                    

                        
भारी परमाणु

                        
32

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
A valerate ester of hydrocortisone used as a moderate-potency topical corticosteroid for inflammatory skin conditions such as atopic dermatitis, psoriasis, and seborrheic dermatitis. The valerate ester increases skin penetration compared to plain hydrocortisone, providing more effective anti-inflammatory action at the site of application. It is available in cream and ointment forms for external application.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Applied directly to the skin or mucous membranes, where it exerts its therapeutic effect locally at the site of application with minimal systemic absorption.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Hydrocortisone Valerate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1200562.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 5282494.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.