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Kanamycin Sulfate

CHEMBL1446 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
582.6 g/mol
LogP
—
Phase
4

The sulfate salt form of kanamycin, an aminoglycoside antibiotic used to treat tuberculosis and other serious bacterial infections. It shares the same mechanism as the parent compound but in a salt form more suitable for pharmaceutical preparation.

आणविक भार

582.6000 g/mol

TPSA

366.00 Ų

चिकित्सीय क्षेत्र

अग्नाशय कैंसर अनिद्रा उच्च रक्तचाप ओवेरियन कैंसर कोलोरेक्टल कैंसर क्रॉनिक किडनी डिज़ीज़ क्षय रोग (ट्यूबरकुलोसिस) ग्लूकोमा जनरलाइज़्ड एंग्ज़ाइटी डिसऑर्डर थायरॉइड कैंसर दर्द प्रबंधन दीर्घकालिक दर्द नॉन-स्मॉल सेल लंग कैंसर प्रोस्टेट कैंसर बाइपोलर डिसऑर्डर माइग्रेन मिर्गी (एपिलेप्सी) मूत्राशय कैंसर सिज़ोफ्रेनिया स्तन कैंसर हृदय विफलता

क्रिया का तंत्र

Binds irreversibly to the 30S ribosomal subunit, causing misreading of mRNA codons and inhibition of translocation. This leads to production of aberrant proteins and disruption of the bacterial cell membrane.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Binds irreversibly to the 30S ribosomal subunit, causing misreading of mRNA codons and inhibition of translocation. This leads to production of aberrant proteins and disruption of the bacterial cell membrane.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
NC[C@H]1O[C@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O)[C@H](N)C[C@@H]2N)[C@H](O)[C@@H](O)[C@@H]1O.O=S(=O)(O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C18H36N4O11.H2O4S/c19-2-6-10(25)12(27)13(28)18(30-6)33-16-5(21)1-4(20)15(14(16)29)32-17-11(26)8(22)9(24)7(3-23)31-17;1-5(2,3)4/h4-18,23-29H,1-3,19-22H2;(H2,1,2,3,4)/t4-,5+,6-,7-,8+,9-,10-,11-,12+,13-,14-,15+,16-,17-,18-;/m1./s1

                

                

                

                    
                    

                        
Molecular Formula

                        
C18H38N4O15S

                    

                    
                    

                        
HBD / HBA

                        
13 / 19

                    

                    
                    

                        
घूर्णनीय बंधन

                        
6

                    

                    
                    
                    

                        
भारी परमाणु

                        
38

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
The sulfate salt form of kanamycin, an aminoglycoside antibiotic used to treat tuberculosis and other serious bacterial infections. It shares the same mechanism as the parent compound but in a salt form more suitable for pharmaceutical preparation.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Binds irreversibly to the 30S ribosomal subunit, causing misreading of mRNA codons and inhibition of translocation. This leads to production of aberrant proteins and disruption of the bacterial cell membrane.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Kanamycin Sulfate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL1446.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 441374.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.