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Ketorolac

CHEMBL469 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
255.3 g/mol
LogP
1.9
Phase
4

A potent NSAID used for short-term management of moderate to severe pain, including postoperative pain and pain associated with certain cancers. It is available in oral, injectable, and nasal spray forms and works by blocking prostaglandin synthesis.

आणविक भार

255.2700 g/mol

LogP

1.90

TPSA

59.30 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

अग्नाशय कैंसर उच्च रक्तचाप एज-रिलेटेड मैक्युलर डिजनरेशन ओवेरियन कैंसर कोलोरेक्टल कैंसर क्रॉनिक किडनी डिज़ीज़ गाउट (गठिया) ग्लूकोमा टाइप 2 मधुमेह डीप वेन थ्रोम्बोसिस / पल्मोनरी एम्बोलिज़्म दर्द प्रबंधन दीर्घकालिक दर्द नॉन-स्मॉल सेल लंग कैंसर प्रसूति एवं स्त्री रोग प्रोस्टेट कैंसर माइग्रेन मोटापा यूरोलॉजी लिम्फोमा ल्यूकेमिया स्तन कैंसर

क्रिया का तंत्र

Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
Embed this structure

                        

                        

                            
                            
                        

                    

                

                

                
                

                    
SMILES

                    
O=C(c1ccccc1)c1ccc2n1CCC2C(=O)O

                

                

                
                

                    
InChI

                    
InChI=1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)

                

                

                

                    
                    

                        
Molecular Formula

                        
C15H13NO3

                    

                    
                    

                        
HBD / HBA

                        
1 / 3

                    

                    
                    

                        
घूर्णनीय बंधन

                        
3

                    

                    
                    
                    

                        
भारी परमाणु

                        
19

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
A potent NSAID used for short-term management of moderate to severe pain, including postoperative pain and pain associated with certain cancers. It is available in oral, injectable, and nasal spray forms and works by blocking prostaglandin synthesis.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Inhibits cyclooxygenase (COX-1 and/or COX-2) enzymes, reducing the synthesis of prostaglandins and thromboxanes from arachidonic acid. This produces anti-inflammatory, analgesic, and antipyretic effects.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Ketorolac is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
  • 
            
            
                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL469.
                Open-access bioactivity database.
            
        
    • 
        
        
        
  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 3826.
                Chemical information database.
            
        
    • 
        
        
        
        
    

    
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.