Levomethadyl Acetate
A long-acting opioid used for the treatment of opioid dependence, providing up to 72 hours of relief from withdrawal symptoms with less frequent dosing than methadone. It was withdrawn from markets due to cardiac side effects.
आणविक भार
353.5000 g/mol
LogP
4.30
TPSA
29.50 Ų
लिपिंस्की RO5
उत्तीर्ण
क्रिया का तंत्र
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission …
2D संरचना
Cite this structure
Embed this structure
SMILES
CC[C@H](OC(C)=O)C(C[C@H](C)N(C)C)(c1ccccc1)c1ccccc1
InChI
InChI=1S/C23H31NO2/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21/h7-16,18,22H,6,17H2,1-5H3/t18-,22-/m0/s1
Molecular Formula
C23H31NO2
HBD / HBA
- / 3
घूर्णनीय बंधन
9
भारी परमाणु
26
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
A long-acting opioid used for the treatment of opioid dependence, providing up to 72 hours of relief from withdrawal symptoms with less frequent dosing than methadone. It was withdrawn from markets due to cardiac side effects.
Binds to mu (μ), kappa (κ), and/or delta (δ) opioid receptors in the central and peripheral nervous system, mimicking endogenous endorphins. Activation of these G-protein-coupled receptors inhibits pain signal transmission and modulates the emotional response to pain.
Yes, Levomethadyl Acetate is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL1514. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 15130. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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