Lorazepam
A benzodiazepine used to treat anxiety disorders, status epilepticus, insomnia, and agitation, and studied as a sedative in critically ill patients. It enhances GABA activity in the brain, producing calming, sedating, and anticonvulsant effects.
आणविक भार
321.1580 g/mol
LogP
2.40
TPSA
61.70 Ų
लिपिंस्की RO5
उत्तीर्ण
चिकित्सीय क्षेत्र
दवा वर्ग
क्रिया का तंत्र
Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.
Pharmacokinetics (PK)
Pharmacodynamics (PD)
Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.
2D संरचना
Cite this structure
Embed this structure
SMILES
O=C1Nc2ccc(Cl)cc2C(c2ccccc2Cl)=NC1O
InChI
InChI=1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)
Molecular Formula
C15H10Cl2N2O2
HBD / HBA
2 / 3
घूर्णनीय बंधन
1
भारी परमाणु
21
No targets recorded
Target interaction data is not yet available for this drug.
No interactions recorded
Drug interaction data is not yet available for this compound.
No side effects recorded
Side effect data is not yet available for this drug.
अक्सर पूछे जाने वाले प्रश्न
A benzodiazepine used to treat anxiety disorders, status epilepticus, insomnia, and agitation, and studied as a sedative in critically ill patients. It enhances GABA activity in the brain, producing calming, sedating, and anticonvulsant effects.
Intermediate-acting benzodiazepine enhancing GABA-A receptor chloride conductance.
Key pharmacokinetic parameters for Lorazepam: Half-life: 10-20 hours.
Yes, Lorazepam is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.
Related Drugs
References & Data Sources
- ChEMBL — European Bioinformatics Institute (EBI). CHEMBL580. Open-access bioactivity database.
- PubChem — National Center for Biotechnology Information (NCBI). CID 3958. Chemical information database.
Data aggregated from publicly available pharmacological databases. Last updated 2026-03-04.
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