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Mebendazole

CHEMBL685 Phase 4 अनुमोदित Small molecule
Half-Life
—
Bioavailability
—
Protein Binding
—
Molecular Weight
295.3 g/mol
LogP
2.8
Phase
4

An antiparasitic medication primarily used to treat intestinal worm infections such as pinworms, roundworms, and hookworms, and is also being studied for potential anticancer properties. It works by disrupting the formation of microtubules in parasites and potentially in cancer cells.

आणविक भार

295.2900 g/mol

LogP

2.80

TPSA

84.10 Ų

लिपिंस्की RO5

उत्तीर्ण

चिकित्सीय क्षेत्र

अग्नाशय कैंसर उच्च रक्तचाप ओवेरियन कैंसर कोलोरेक्टल कैंसर थायरॉइड कैंसर नॉन-स्मॉल सेल लंग कैंसर प्रोस्टेट कैंसर मलेरिया मूत्राशय कैंसर मेलानोमा मोटापा स्तन कैंसर

क्रिया का तंत्र

Disrupts microtubule dynamics by binding to tubulin, preventing the formation of the mitotic spindle and arresting cell division at metaphase. This induces apoptosis in rapidly dividing cells.

Pharmacokinetics (PK)

Pharmacodynamics (PD)

तंत्र

Disrupts microtubule dynamics by binding to tubulin, preventing the formation of the mitotic spindle and arresting cell division at metaphase. This induces apoptosis in rapidly dividing cells.

2D संरचना

SVG PNG

Cite this structure


                        

                            
                            
                        

                    

                


                
                

                    

                    

                        
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SMILES

                    
COC(=O)Nc1nc2cc(C(=O)c3ccccc3)ccc2[nH]1

                

                

                
                

                    
InChI

                    
InChI=1S/C16H13N3O3/c1-22-16(21)19-15-17-12-8-7-11(9-13(12)18-15)14(20)10-5-3-2-4-6-10/h2-9H,1H3,(H2,17,18,19,21)

                

                

                

                    
                    

                        
Molecular Formula

                        
C16H13N3O3

                    

                    
                    

                        
HBD / HBA

                        
2 / 4

                    

                    
                    

                        
घूर्णनीय बंधन

                        
4

                    

                    
                    
                    

                        
भारी परमाणु

                        
22

                    

                    
                

            


            
            

                
                


    
    
        
    
    
    
No targets recorded

    
    
Target interaction data is not yet available for this drug.

    



                
            


            
            

                
                


    
    
        
    
    
    
No interactions recorded

    
    
Drug interaction data is not yet available for this compound.

    



                
            


            
            

                
                


    
    
        
    
    
    
No side effects recorded

    
    
Side effect data is not yet available for this drug.

    



                
            


            
            
            

                
अक्सर पूछे जाने वाले प्रश्न

                

                    
                    

                        
                        

                            
An antiparasitic medication primarily used to treat intestinal worm infections such as pinworms, roundworms, and hookworms, and is also being studied for potential anticancer properties. It works by disrupting the formation of microtubules in parasites and potentially in cancer cells.

                        

                    

                    

                    

                    
                    

                        
                        

                            
Disrupts microtubule dynamics by binding to tubulin, preventing the formation of the mitotic spindle and arresting cell division at metaphase. This induces apoptosis in rapidly dividing cells.

                        

                    

                    

                    

                    

                        
                        

                            
Yes, Mebendazole is an approved drug. It has reached clinical phase 4. It is classified as a Small molecule.

                        

                    

                

            

            

            
            

            
            

            
            
{# References & Data Sources section for drug detail pages.
   Renders standard pharmacological database links plus the drug's data_sources field. #}


    
References & Data Sources

    
    
        
        
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                ChEMBL — European Bioinformatics Institute (EBI).
                CHEMBL685.
                Open-access bioactivity database.
            
        
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  • 
            
            
                PubChem — National Center for Biotechnology Information (NCBI).
                CID 4030.
                Chemical information database.
            
        
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Data aggregated from publicly available pharmacological databases. Last updated 2026-03-28.




        


        
        
    


    



    
चिकित्सा अस्वीकरण

    

        This content is for educational and informational purposes only. It is not a substitute for professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before making medication decisions.
    

    

        Data sources:
        ChEMBL,
        PubChem,
        DailyMed.